New Longevity Formula for younger-looking skin, for longer. Caudalie Premier Cru The Cream Refill is the exceptional anti-aging treatment that corrects the 8 signs of aging: wrinkles, loss of firmness, volume and elasticity, spots, dehydration and loss of radiance. Caudalie Premier Cru The Cream Refill leaves skin visibly firmer, smoother and more radiant.